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Zohre Delshadian

Zohre Delshadian

Lorestan University of Medical Sciences, Iran


Zohre Delshadian has her expertise in working on a kind of bioactive peptides derived from bovine milk casein, throughout her PhD dissertation. Casein Phosphopeptides (CPPs) are biologically active peptides that have the ability to bind with bivalent minerals, such as Fe+2 and increase their bioavailability while keeping them soluble in the intestinal tract. The low bioavailability of the most commonly used iron preparation for fortification, ferrous sulfate, is known for its poor solubility at the alkaline pH of the intestine. Therefore, by using casein phosphopeptides bound to iron instead of ferrous sulfate in fortified foods, the defect of the low bioavailability of iron could be principally solved. She has discovered the optimized experimental conditions (pH, mass ratio of iron to CPP (MR) and holding time) for the better binding of ferrous iron to casein phosphopeptides, using response surface methodology.



Abstract : Iron-binding optimization of bioactive casein phosphopeptides using response surface methodology; effect of pH, mass ratio and time